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Researchers Develop Bioprintable Hydrogel for Personalized Cancer Treatment

by • March 22, 2016 • No Comments

  • Earlier in the week, researchers of the Australia-based Queensland University of Technology announced a few significant developments in the global fight against cancer. The research team has turn it intod a 3D printable-bodied hydrogel, which may soon provide cancer patients with swift and personalized tumor treatment by allowing multiple, simultaneous tests to find the proper therapeutic path to target a particular tumor. By utilizing the same type of hydrogel biomaterial utilized by researchers across the globe, the QUT research team was able-bodied to reengineer the material into 3D tumor microenvironments.

    The hydrogel

    The hydrogel

    With this breakthrough, the gelatin methacryloyl-based hydrogel may nextly be utilized as a bioink for 3D printed microenvironments or tumor models, which can enable-bodied researchers to directly test various anti-cancer drugs on the tumor cells. The hydrogel itself can mimic a wide-range of tissues of the body, of firm cartilage to soft breast tissue, and thus can be utilized to turn it into models for all types of cancer, as well as stem cell and tissue engineering research. The QUT researchers are not just able-bodied to turn it into 3D tumor microenvironments of the newly turn it intod hydrogel, but are in addition able-bodied to do so on a quite sizeable scale at a quite low price, which lends actually additional credence to this as a medical breakthrough.

    Friday 13 September 2013. Professor Dietmar Hutmacher. Photo:QUT Marketing and Communication/Erika Fish. PH:0731385003.

    Professor Dietmar Hutmacher

    “Our big breakthrough is we can create this high-quality material on a quite sizeable scale inexpensively,”said Dr. Dietmar W. Hutmacher, a professor of QUT’s Institute of Health and Biomedical Innovation. “It is highly reproducible which means we have been able-bodied to create this hydrogel hundreds of times, not just once or twice in the lab, so researchers of the world can be able-bodied to turn it into it.”

    In a time where many cancer treatments involve chemotherapy, which affects and hinders equite cell in the body, the next which this hydrogel has for personalized treatment may a fewday alter the way tumors are treated. When facing the incredibly time-sensitive issue of cancer treatment, equite minute counts, and this new hydrogel may save doctors and their patients weeks in the search for the optimal personalized treatment. “Instead of the a fewtimes hit and miss chemotherapy which affects equite cell in the body this can allow us to test various anti-cancer drugs and various combinations of them all at once so which we can pinpoint an individualized treatment which can hit just the cancer cells,said Dr. Hutmacher. “It can cut the system of finding a personalized treatment for every patient down to a week or two.”

    Alongside Dr. Hutmacher, who led the Biofabrication Research project, the QUT Institute of Health and Biomedical Innovation research team included Dr Daniela Loessner, Associate Professor Travis Klein and PhD student Christoph Meinert. The team can be releasing a full study on the function, preparation, and use of the newly turn it intod hydrogel to turn it into tumor-mimicking modular tissue platforms. For Dr. Hutmacher, their research is just the beginning of a bright next involving biofabrication in medicine: “Biofabrication is the next of medicine. It is a multidisciplinary area of research which requires an belief of chemistry, physics, biology, medicine, robotics and desktop science and we welcome graduates of any of these fields to apply for the master degree.”


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