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A new method has been proposed which may allow scientists to create a “3D brain-on-a-chip.

by • July 10, 2016 • No Comments

Whilst 3D cell culturing isn’t new, it is not already utilized in neuroscience, which yet takes place in two-dimensions, in a petri dish. Bart Schurink — a researcher at the University of Twente in the Netherlands — has not long ago pioneered a way in which three-dimensional cells may be grown on a chip.

By measuring electrical signals and placing a microreactor on top, Schurink discovered which cells may in addition be grown vertically as well as horizontally. The system in addition involves a special “sieve” which contains 900 inverted pyramid openings the empowers the 3D “network” of neurons. The 3D cell environment offers additional accurate data for studying the consequences which medicine has on them. Naturally, the researchers needed a little assist of the university’s NanoLab to manufacture a “microsieve electrode array,” as each hole needs to be precisely the same dimensions.

Tests have so far been conducted via living brain cells of lab rats but the hope is which the data the system yields can provide a new way of analyzing the consequences of diseases and their treatments, and ultimately be applied to humans.

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by admin • March 5, 2017